: Research: Amanda Blackford Sc.M.


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Johns Hopkins Medicine | Sidney Kimmel Comprehensive Cancer Center

Amanda Blackford Sc.M.

Research Summary: Amanda has been a member of the Division of Biostatistics and Bioinformatics since 2003. During that time she has collaborated on a wide array of research topics, including developing models for predicting who may carry a cancer susceptibility gene, with specific applications to familial breast, ovarian, colorectal, endometrial, pancreas and skin cancers through the BayesMendel group. She also currently maintains the R package for implementing those models, which have been used by genetic counselors all over the world. Amanda also has experience with large, multi-center Phase III clinical trials through collaborations with the Center for Clinical Trials in the Bloomberg School of Public Health. She is currently the biostatistician for an ongoing clinical trial in this group with a Bayesian adaptive randomization design. Other areas in which she has expertise include working with SEER-Medicare administrative claims data, patient-reported outcomes research projects, and Medicaid and state-specific all-payer administrative claims data. However, the majority of Amanda's research and collaboration is set in the SKCCC, specifically in the design, monitoring, and analysis of Phase I and II clinical trials.
Keywords: risk prediction, BayesMendel, brcapro, early phase clinical trials, SEER-Medicare, PROs