: Research: Zheyu Wang Ph.D.


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Johns Hopkins Medicine | Sidney Kimmel Comprehensive Cancer Center

Zheyu Wang Ph.D.

Research Summary: My primary research interest is in statistical methods for medical diagnosis and biomarker evaluation. In particular, I'm interested in the situation where the disease status may be ordinal, and this true disease status, also called the 'gold standard', is unknown due to time/cost constraints, measurement errors or ethical concerns. I've been working on finite mixture models and latent variable models to address these issues. I'm also interested in risk prediction, specifically, in estimation and inference of the incremental values for risk prediction introduced by novel biomarkers or additional risk factors. Recently, I've developed interests in time dependent diagnosis and diagnosis with potentially high dimensional features, such as imaging.
Keywords: Diagnostic testing, biomarkers evaluation, risk prediction, unknown gold standard, cancer, Alzheimer's disease, traditional Chinese medicine